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PUBLICATIONS

RESEARCH MANUSCRIPTS

A conformational selection mechanism of flavivirus NS5 for species-specific STAT2 inhibition

Biswal, M., Yao, W., Lu, J., Chen, J., Morrison, J., Hai, R., & Song, J. A conformational selection mechanism of flavivirus NS5 for species-specific STAT2 inhibition.

Communications Biology. 2024

Pleural macrophages promote recovery from influenza virus infection.

Stumpff JP 2nd, Kim SY, McFadden MI, Nishida A, Shirazi R, Steuerman Y, Gat-Viks I, Forero A, Nair MG, Morrison J. Pleural macrophages translocate to the lung during infection to promote improved influenza outcomes.

PNAS. 2023

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Immunological and pathological landscape of dengue serotypes 1-4 infections in immune-competent mice.

Abhay P. S. Rathore, Chinmay K. Mantri, Meredith W. Tan, Roksana Shirazi, Andrew Nishida, Siti A. B. Aman, Juliet Morrison, Ashley L. St John.

Frontiers in Immunology. 2021.

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Attacking COVID-19 progression using multi-drug therapy for synergetic target engagement.

Coban M, Morrison J, Maharjan S, Hernandez Medina DH, Li W, Zhang YS, Freeman WD, Radisky ES, Le Roch KG, Weisend CM, Ebihara H, Caulfield TR.

Biomolecules. 2021.

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Laboratory-developed test for SARS-CoV-2 using saliva samples at the University of California, Riverside.

Hai R, Collin M, Tsau S, Raygoza D, Morrison J, Carrillo AJ, Collier LA, Bayubay W, Han K, Kaloshian I, Borkovich KA.

MedRxiv. 2021.

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DEvis: an R package for aggregation and visualization of differential expression data.

Price A, Caciula A, Guo C, Lee B, Morrison J, Rasmussen A, Lipkin WI, Jain K.

BMC Bioinformatics. 2019.

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Host-specific NS5 ubiquitination determines yellow fever virus tropism.

Miorin L, Laurent-Rolle M, Pisanelli G, Co PH, Albrecht RA, García-Sastre A, Morrison J.

J Virol. 2019.

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An immunocompetent mouse model of Zika virus infection.

Gorman MJ, Caine EA, Zaitsev K, Begley MC, Weger-Lucarelli J, Uccellini MB, Tripathi S, Morrison J, Yount BL, Dinnon III KH, Rückert C, Young MC, Zhu Z, Robertson SJ, McNally KL, Ye J, Cao B, Mysorekar IU, Ebel GB, Baric RS, Best SM, Artyomov MN, García-Sastre A, Diamond MS.

Cell Host Microbe. 2018.

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Transcriptional profiling confirms the therapeutic effects of mast cell stabilization in a dengue disease model.

Morrison J, Rathore APS, Mantri CK, Aman SAB, Nishida A, St John AL.

J Virol. 2017.

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Early nasopharyngeal microbial signature associated with severe influenza in children: a retrospective pilot study.

Langevin S, Pichon M, Smith E, Morrison J, Bent Z, Green R, Barker K, Solberg O, Gillet Y, Javouhey E, Lina B, Katze MG, Josset L.

J Gen Virol. 2017.

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Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates.

Koday MT, Leonard JA, Munson P, Forero A, Koday M, Bratt DL, Fuller JT, Murnane R, Qin S, Todd A. Reinhart TA, Duus K, Messaoudi I, Hartman AL, Stefano-Cole K, Morrison J, Katze MG, Fuller DH.

PLoS One. 2017.

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Evaluation of the innate immune responses to influenza and live-attenuated influenza vaccine infection in primary differentiated human nasal epithelial cells.

Forero A, Fenstermacher K, Wohlgemuth N, Nishida A, Carter V, Smith EA, Peng X, Hayes M, Francis D, Treanor J, Morrison J, Klein SL, Lane A, Katze MG, Pekosz A.

Vaccine. 2017.

Anomaly detection in host signaling pathways for the early prognosis of acute infection.

Wang K, Langevin S, O'Hern CS, Shattuck MD, Ogle S, Morrison J, Slayden R, Katze MG, Kirby M.

PLoS One. 2016.

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Integrated Omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: The crucial role of lipid metabolism.

Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger S, Hatta M, Morrison J, Zink EM, Kim YM, Schepmoes AA, Purvine SO, Weitz KK, Green RR, Tilton SC, Webb-Robertson BJ, Waters KM, Metz TO, Smith RD, Kawaoka Y, Suresh M, Josset L, Katze MG.

Cell Host Microbe. 2016.

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La Piedad Michoacan Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation.

Pisanelli G, Laurent-Rolle M, Manicassamy B, Belicha-Villanueva A, Morrison J, Lozano-Dubernard B, Castro-Peralta F, Iovane G, García-Sastre A.

Virus Res. 2016.

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The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice.

Forero A, Tisoncik-Go J, Watanabe T, Zhong G, Hatta M, Tchitchek N, Selinger C, Chang J, Barker K, Morrison J, Berndt J, Moon R, Josset L, Kawaoka Y, Katze MG.

J Virol. 2015.

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Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression.

Xiong H, Morrison J, Ferris MT, Gralinski LE, Whitmore AC, Green RR, Thomas MJ, Tisoncik-Go J, Schroth GP, Pardo-Manuel de Villena F, Baric RS, Heise MT, Peng X, and Katze MG.

G3 (Bethesda). 2014.

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Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKepsilon kinase-mediated antiviral response.

Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martınez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, and García-Sastre A.

Immunity. 2014.

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H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice.

Morrison J, Josset L, Tchitchek N, Chang J, Belser JA, Swayne DE, Pantin-Jackwood MJ, Tumpey TM, Katze MG.

J Virol. 2014.

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MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling.

Lin F*, Morrison JM*, Wu W*, Worman HJ.

Hum Mol Genet. 2005. *authors contributed equally

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COMMENTARIES AND OP-EDS

Virology—the path forward

Angela L. Rasmussen, Gigi K. Gronvall, Anice C. Lowen , Felicia Goodrum, et al.
Journal of Virology. 2024

When do I need a Covid face mask?

Linsey Marr, Juliet Morrison, and Caitlin Rivers.

New York Times. 05/2021

I got my Covid vaccine. Now can I hug my mom?

Linsey Marr, Juliet Morrison, and Caitlin Rivers.

New York Times. 03/2021

Commentaries and Op-Eds

Book Chapters and Reviews

Innate immunity and flavivirus infection.

Laurent-Rolle M, Morrison J, Garcia-Sastre A

In: Molecular Virology and Control of Flaviviruses. Caister Academic Press; 2012.

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PUBLICATIONS

RESEARCH MANUSCRIPTS

A conformational selection mechanism of flavivirus NS5 for species-specific STAT2 inhibition

Pleural macrophages promote recovery from influenza virus infection.

Immunological and pathological landscape of dengue serotypes 1-4 infections in immune-competent mice.

Attacking COVID-19 progression using multi-drug therapy for synergetic target engagement.

Laboratory-developed test for SARS-CoV-2 using saliva samples at the University of California, Riverside.

DEvis: an R package for aggregation and visualization of differential expression data.

Host-specific NS5 ubiquitination determines yellow fever virus tropism.

An immunocompetent mouse model of Zika virus infection.

Transcriptional profiling confirms the therapeutic effects of mast cell stabilization in a dengue disease model.

Early nasopharyngeal microbial signature associated with severe influenza in children: a retrospective pilot study.

Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates.

Evaluation of the innate immune responses to influenza and live-attenuated influenza vaccine infection in primary differentiated human nasal epithelial cells.

Anomaly detection in host signaling pathways for the early prognosis of acute infection.

Integrated Omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: The crucial role of lipid metabolism.

La Piedad Michoacan Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation.

The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice.

Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression.

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKepsilon kinase-mediated antiviral response.

H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice.

The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon.

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.

Mouse STAT2 restricts early dengue virus replication.

Proteinase 2Apro is essential for enterovirus replication in type I interferon-treated cells.

MDA-5 is cleaved in poliovirus-infected cells.

MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling.

COMMENTARIES AND OP-EDS

Virology—the path forward

When do I need a Covid face mask?

I got my Covid vaccine. Now can I hug my mom?

BOOK CHAPTERS AND REVIEWS

Contributions of ubiquitin and ubiquitination to flaviviral antagonism of type I IFN.

The role of NS5 protein in determination of host cell range for yellow fever virus.

Viral vaccines and systems vaccinology.

Gene expression signatures as a therapeutic target for severe H7N9 influenza - what do we know so far?

STAT2 signaling and dengue virus infection.

Innate immunity evasion by dengue virus.

Innate immunity and flavivirus infection.